ZFIN Image: Powell et al., 2016, Fig. 7

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Figure Caption

Fig. 7

Wtip is required for early left-right patterning. Dorsal views, anterior to the bottom of the panels. (A-D,K) lefty1 and lefty2, (E-H,L) spaw and (I,J,M) bmp4 expressions in (A-J) 22-somite stage embryos. Normally, (A,E,I) left1+2, spaw and bmp4 transcripts expressed in the left cardiac lateral plate mesoderm, (B,F,J) have bilateral, (C,G) right and (D,H) absent expression in wtip morphants (1.035 pmol/embryo). Bar chart details the left-right patterning for control and wtip morphants. Wtip, Wilm′s tumor 1 interacting protein; lefty1, left right determination factor 1; spaw, southpaw; bmp4, bone morphogenic factor 4; conMO, control morpholino oligonucleotide.

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Acknowledgments

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