Gene

spaw

ID
ZDB-GENE-030219-1
Name
southpaw
Symbol
spaw Nomenclature History
Previous Names
  • ndr3 (2)
  • unm s457
  • unm t30973
  • unm_s457
  • unm_t30973
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have cytokine activity and type I activin receptor binding activity. Involved in determination of left/right symmetry; embryonic heart tube left/right pattern formation; and regulation of BMP signaling pathway involved in heart jogging. Predicted to localize to extracellular space. Is expressed in anterior neural rod; cardiovascular system; diencephalon; mesoderm; and tail bud. Used to study anxiety disorder.
Genome Resources
Note
None
Expression
All Expression Data
163 figures from 130 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
31 figures from 20 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spaw Human Ortholog
No data available
Associated With spaw Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017948 Transforming growth factor beta, conserved site
Domain IPR001111 TGF-beta, propeptide
Domain IPR001839 Transforming growth factor-beta, C-terminal
Family IPR015615 Transforming growth factor-beta-related
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine TGF-beta, propeptide Transforming growth factor beta, conserved site Transforming growth factor-beta, C-terminal Transforming growth factor-beta-related
UniProtKB:F1QX69 411
UniProtKB:Q7ZZT5 404
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations