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Fig. 7 Decreased LRRK2 level affects the abundance of central PD associated proteins. A: Western blot analysis of protein lysates from 3-dpf wt and LRRK2 morphant embryos using antibodies for β-synuclein, SOD1, and PARK13. LRRK2 knockdown causes upregulation of β-synuclein, SOD1, and PARK13. Both actin and GAPDH were used as loading controls. B: Quantification of the Western blot analysis against the GAPDH control. n = 3 for all groups, 12 embryos in each group in each experiment. *P < 0.05, **P < 0.01
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Full text @ J. Neurosci. Res.