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Fig. 4

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Figures for de Preux Charles et al., 2016
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Fig. 4

A single intraperitoneal injection of immunogenic particles triggers the reentry of CMs into the cell cycle. (a-d) Representative heart sections of uninjected transgenic cmlc2:DsRed2-nuc (red) fish controls (a) or injected with Hank′s solution (b), LPS (c) or Zymosan (d) labelled with the cell-cycle marker MCM5 (green). Dashed lines separate compact and trabecular myocardium. Arrows indicate double-positive nuclei. (e,f) Quantification of MCM5-positive CM and non-CM nuclei. (g) Sublocalization of MCM5-positive CMs within the distinct myocardium compartment, the compact (Comp. MC) and trabecular (Trab. MC) myocardium (n ≥ 4 hearts; ≥2 sections per heart; n.s., non-significant; *p < 0.05; ***p < 0.001).

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