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Fig. 1
Decreased expression of tbx2b and nr2e3 in Flh mutants. (A) In situ hybridization showing dorsal views of ascl1a, tbx2b and nr2e3 expression in the pineal anlage of WT, flhn1+/- or flhn1-/- embryos at 10 ss (14hpf). Scale bar: 30µm. (B) Quantification of the number of cells expressing ascl1a, tbx2b or nr2e3 at 10 ss under the indicated genetic backgrounds; mean±s.e.m. and number of samples (n) are shown. ****P<0.0001, **P<0.01, P>0.05 (n.s.), one-way ANOVA with Dunnett′s post-hoc analysis.
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