ZFIN Image: Pagán et al., 2015, Fig. 7

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Figure Caption

Fig. 7

Restoring CSF-1R Signaling during an Ongoing Infection Delays Granuloma Necrosis

(A) Schematic of temperature-shifting experiment.

(B-D) Macrophage numbers (B), bacterial cording (C), and bacterial burdens (D) in phenotypically WT heterozygotes (csf1r^ts/+), csf1r null homozygous mutants (csf1r^-/-), and temperature-sensitive heterozygotes (csf1r^ts/-). Horizontal lines indicate means. Statistical significance was determined by one-way ANOVA with Tukey’s post-test (B and D) or Fisher’s exact test, correcting for multiple comparisons by multiplying p values obtained in pairwise comparisons by the number of groups in each experimental condition (C).

Figure Data

Phenotype details

Acknowledgments

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