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Fig. 4
Initiating SB505124 treatment during mid blastula stages blocks neural tube closure. First column: developmental stage and images of live embryos at the onset of inhibitor exposure. Lateral views with animal pole to the top. Scale bar: 250 µm. Second column: lateral views of whole embryos with anterior to the left and dorsal to the top. Scale bar: 250 µm. Third–fifth column: Embryos were assayed for otx5 expression in the pineal gland. Dorsal views, anterior to the top. Scale bar: 50 µm. Refer to Table 3 for quantitative data.
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