ZFIN Image: Hu et al., 2015, Fig. 8

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Figure Caption

Fig. 8

Increased p21b^CIP1/WAF1 expression in homozygous ddb1^m863 mutants.

(A-B) Enhanced expression of p21b^CIP1/WAF1 (cdkn1a) in ddb1^m863 homozygous embryos in the proliferation regions of the optic tectum, compared to wild type siblings at 36 hpf. (C-D) At 48 hpf, p21b^CIP1/WAF1 expression was strongly elevated in proliferation regions of the optic tectum, cerebellum, telencephalon, retina, branchial arches and pectoral fin bud in ddb1^m863 mutants compared to wild type siblings. In contrast, expression of p21b^CIP1/WAF1 in ventral hindbrain nuclei (arrow heads in B, D) was unaltered in ddb1^m863 mutants. All views are lateral except for inserts (dorsal views). Abbreviations used: Cce, cerebellum; H, hypothalamus; L, lens; pfb, pectal fin bud; ret, retina; tel, telencephalon; TeO, tectum opticum. Anterior towards the left. Scale bar: 100 µm.

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Expression / Labeling details

Acknowledgments

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