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Fig. 3
Abnormal morphology of ambra1 knockdown embryos, as revealed by haematoxylin/eosin staining.
Representative longitudinal sections of 3 dpf control and ambra1 morphant embryos. Myofibers of ATG- and co-injected morphants muscles are highly disorganized and display irregular myosepta boundaries. The phenotype of splice-morphants is much less severe when compared to WT and 5 m-control embryos.
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