ZFIN Image: Forn-Cuní et al., 2014, Fig. 6

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Figure Caption

Fig. 6

Developmental and inflammatory effects of the c3.1 and c3.7/8 inhibition.

(A) MO-c3.1s injected at high concentrations produced aberrant phenotypes and increased mortality. Co-injecting with c3.1 capped mRNA recovered the WT phenotype in a dose-dependent manner (LD: 2,25 ng c3.1 capped RNA; HD: 4,5 ng c3.1 capped RNA). (B) Representative individuals of the c3.1 inhibition treatments and its phenotypic rescue. (C) MO-c3.7/8s microinjected larvae showed a major migration number of neutrophils to the amputation site 3 h after tail clipping (confocal images). Statistical significance was determined by unpaired T-tests (**P<0.01, ***P<0.001). (D) MO-c3.7/8s microinjected larvae significantly expressed higher levels of il1b 3 h after bath infection with A. hydrophila.

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Acknowledgments

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