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Fig. S5
Shh signaling activity is reduced in sulf1-depleted zebrafish embryos. (A-F) Expression of ptch2 at 16hpf (A,D), 24hpf (B,E) and 36hpf (C,F) in embryos injected with ctrlMO (A-C) and sulf1MO (D-F). (G,H) Expression of ptch2 at 24hpf in wild-type (G) and sulf1sa199-/- (H) embryos. Note reduction in ptch2 expression both in sulf1MO-injected and sulf1sa199-/- embryos at 24hpf. Scale bar = 20μm.
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