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Fig. 8 Notochord shape phenotype of mutants in the gul, lev, bup, tri and kny loci A wavy notochord phenotype by 28 hpf characterizes the two mutations gulm208 (A) and levm531 (B). (C) By 72 hpf gulm208 mutants have a straight notchord and a severe head malformation (bottom). (F, F′) By contrast, by 96 hpf in levm531 mutants the wavy notochord phenotype is exacerbated and shows both lateral (F) and dorsal-ventral flexures (F′). The gastrulation mutations trim144 (D) and knym119 (E) exhibit a folded notochord phenotype only in the tail at 72 hpf. Scale bars, 250 μm (A,E, F′) and 1 mm (A,F).
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