ZFIN Image: Porreca et al., 2012, Fig. 4

Image

Figure Caption

Fig. 4 bcl2l expression in the thyroid is positively regulated bypax2a,nk2.1aandhhex. Lateral views with anterior to the left. Stage is indicated at bottom left, genotype or experimental morpholino at bottom right and marker at top right. (A) and (B) bcl2l expression in wild-type (A) and in noi^tu29 embryo (B) showing that bcl2l is not expressed in thyroid primordium when pax2a mRNA translation is inhibited. (C) nk2.1a expression in noi^tu29 embryo shows the presence of the thyroid primordium at this stage. (D) and (E) bcl2l expression in control (D) and nk2.1a morphant embryos (E) showing lack of bcl2l expression in the thyroid of a morphant embryo. Hhex (F) and pax2a (G) expression in nk2.1a morphant embryos shows the presence of the thyroid primordium at this stage. (H) and (I) bcl2l expression in control (H) and hhex morphant embryos (I) showing lack of bcl2l expression in the morphant embryo thyroid primordium. Nk2.1a (J) and pax2a (K) expression in hhex morphant embryos shows the presence of the thyroid primordium at the analyzed stage. Arrow indicates the thyroid primordium; asterisk the hindbrain–mindbrain boundary.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 366(2), Porreca, I., De Felice, E., Fagman, H., Di Lauro, R., and Sordino, P., Zebrafish bcl2l is a survival factor in thyroid development, 142-152, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.