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Fig. 8 Chd7 is important for cranial ganglia development and proper projection of facial nerves.
Dorsal view (rostal towards the top) of confocal fluorescent composite images of hindbrain branchiomotor neurons in control-MO injected (A) and chd7-MO-injected (B) 48 hpf Isl1-GFP transgenic embryos. (C, D) Confocal fluorescent composite images showing anti-3A10 antibody-stained axons of 48 hpf embryos. The broken lines indicate the area of significant loss of VII nerves in chd7 morphants. nV, trigeminal motoneurons; Va, anterior trigeminal motoneurons; Vp, posterior trigeminal motoneurons; nVII, facial motoneurons; nX, Vagal motoneurons; V, trigeminal nerve; VII, facial nerve. Scale bar: 50 μm.