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Fig. S4 Induction of p53 mRNA expression in LA1908 mutant embryos. A–B, Expression of p53 mRNA is strongly induced by loss of utp15. Upregulation is observed in all tissues in mutant (B) relative to wildtype (A) embryos. C–D, Vibratome cross-section of embryos shown in Figure 6 F–G, revealing induction of thbs1, particularly in the dorsolateral roof and floor plate of the neural tube.
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