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Fig. S3 p53 MO blocks nervous system necrosis but does not affect melanophore development. Lateral views of live zebrafish embryos at 36 hpf. Insets show higher magnification of melanophores contained in white boxes. (A) A wild-type embryo shows normal melanophore development, similar to embryos injected with tfap2e e3i3 MO (B,C). (B) The embryo injected with tfap2e MO also displays signs of central nervous system cell death (i.e., patches of opacity in the brain and spinal cord, white asterisk), which is reversed (C) by co-injection of a p53 MO.
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