ZFIN Image: Vaccari et al., 2010, Fig. 6

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Figure Caption

Fig. 6 aldh1a2 and hoxb1b expression is regulated by prep1.2. A–H: Starting from 15 somites to 24 hpf the expression of aldh1a2 in embryos injected with MO1-prep1.2 is reduced in branchial arches (black arrowhead), while aldh1a2 expression is unaffected in the trunk. In situ hybridization of 24 hpf embryos shows that aldh1a2 expression is lost also in pectoral fin bud (*) of prep1.2 morphant embryos. I–L: At 24 hpf hoxb1b expression is downregulated in branchial arches of prep1.2 morphant embryos. M, N: hoxb1b expression is unaffected at early developmental stages in MO1-prep1.2 injected embryos. Non-specific toxic effects of morpholino were excluded by co-injecting MO-p53 (H and L). ov: otic vesicle; pba: prospective branchial arches; pfb: prospective fin bud.

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Acknowledgments

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Reprinted from Developmental Biology, 343(1-2), Vaccari, E., Deflorian, G., Bernardi, E., Pauls, S., Tiso, N., Bortolussi, M., and Argenton, F., prep1.2 and aldh1a2 participate to a positive loop required for branchial arches development in zebrafish, 94-103, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.