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Fig. 5 Midline mutants disrupt heart and gut asymmetries. Dorsal views of whole-mounted wild-type (A–C), flh (D–F), and oep (G–I) mutant embryos, anterior to the top, except middle panels which are anterior views with dorsal to the top. (A, D, G) BMP4 expression in the primitive heart tube. (B, E, H) DM-GRASP expression in the ventricle (arrows). (C, F, I) DM-GRASP expression in the hepatic diverticulum (arrows). Scale bars, 100 μm.
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Reprinted from Developmental Biology, 210(2), Schilling, T.F., Concordet, J.-P., and Ingham, P.W., Regulation of left-right asymmetries in the zebrafish by Shh and BMP4, 277-287, Copyright (1999) with permission from Elsevier. Full text @ Dev. Biol.