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Fig. 7 Patterning of the spinal cord is affected in the gir mutant. Expression of hoxb4a and krox20 (A and B), hoxb5a and krox20 (C and D), and hoxb6a and krox20 (E and F) in wild type (A, C, and E) and gir mutant (B, D, and F) embryos at 20 hpf. Expression of these hox genes is upregulated and the expression domains of hoxb5a and hoxb6a are markedly expanded rostrally in the gir mutant. Genotypes were determined by PCR assay after the photographs had been taken.
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Reprinted from Developmental Biology, 278(2), Emoto, Y., Wada, H., Okamoto, H., Kudo, A., and Imai, Y., Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish, 415-427, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.