Gene

hoxb4a

ID

ZDB-GENE-990415-105

Name

homeobox B4a

Symbol

hoxb4a Nomenclature History

Previous Names

hoxb4
etID309956.3 (1)
sb:eu512
Z-17
ZF-13
zf13

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and activating transcription factor binding activity. Predicted to be involved in anterior/posterior pattern specification and embryonic skeletal system morphogenesis. Predicted to localize to nucleus. Is expressed in several structures, including hindbrain neural keel; nervous system; neural rod; pharyngeal arch; and somite. Orthologous to human HOXB4 (homeobox B4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

43 figures from 29 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu512 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hoxb4a Human Ortholog

No data available

Associated With hoxb4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001827	Homeobox protein, antennapedia type, conserved site
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeobox domain
Domain	IPR020479	Homeobox domain, metazoa
Family	IPR017995	Homeobox protein, antennapedia type
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily

Domain Details Per Protein

Protein	Length	Homeobox, conserved site	Homeobox domain	Homeobox domain, metazoa	Homeobox-like domain superfamily	Homeobox protein, antennapedia type	Homeobox protein, antennapedia type, conserved site
UniProtKB:B3DHP6 InterPro	246
UniProtKB:P22574 InterPro	246
UniProtKB:Q0D251 InterPro	105

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	hoxb4a-201 (1) Ensembl	1235 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	hoxb4a-202 (1) Ensembl	529 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ottdart00000001816 (1)	1333 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Addgene:pGEM-T ZfHoxb4a

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations