Gene
hoxb4a
- ID
- ZDB-GENE-990415-105
- Name
- homeobox B4a
- Symbol
- hoxb4a Nomenclature History
- Previous Names
-
- hoxb4
- etID309956.3 (1)
- sb:eu512
- Z-17
- ZF-13
- zf13
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in several structures, including hindbrain neural keel; nervous system; neural rod; pharyngeal arch; and somite. Orthologous to human HOXB4 (homeobox B4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 43 figures from 29 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu512 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001827 | Homeobox protein, antennapedia type, conserved site |
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR020479 | Homeodomain, metazoa |
| Family | IPR017995 | Homeobox protein, antennapedia type |
| Family | IPR050609 | Antp homeobox family, Deformed subfamily |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Antp homeobox family, Deformed subfamily | Homedomain-like superfamily | Homeobox, conserved site | Homeobox protein, antennapedia type | Homeobox protein, antennapedia type, conserved site | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:P22574 | InterPro | 246 | |||||||
| UniProtKB:B3DHP6 | InterPro | 246 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hoxb4a-201
(1)
|
Ensembl | 1,235 nt | ||
| mRNA |
hoxb4a-202
(1)
|
Ensembl | 529 nt | ||
| mRNA | ottdart00000001816 (1) | Havana | 1,333 nt |
Interactions and Pathways
No data available
Plasmids