Fig. 5 Cooperation of FGF and Wnt signaling for the cdx1a and cdx4 expression. Expression of cdx1a and cdx4 at the 3-somite stage in wild-type embryos (wt, A, B), SU5402 (an inhibitor of FGF receptors)-treated embryos (C, D), a dominant negative Xenopus FGF receptor 1 (XFD) RNA (500 pg)-injected embryos (E, F), SU5402-treated wnt3a/wnt8 morphant embryos (G, H), and embryos receiving an injection of 6 pg of pCS2 + fgf8 (I, J). The cdx1a and cdx4 expression was slightly reduced in the SU5402-treated embryos, and more strongly reduced in the embryos defective in both Wnt3a/Wnt8 and FGF signaling. In contrast, expression of cdx1a and cdx4 was expanded anteriorly in the fgf8-misexpressing embryos. Lateral views with dorsal to the right.
Reprinted from Developmental Biology, 279(1), Shimizu, T., Bae, Y.K., Muraoka, O., and Hibi, M., Interaction of Wnt and caudal-related genes in zebrafish posterior body formation, 125-141, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.