Gene

cdx1a

ID
ZDB-GENE-050510-1
Name
caudal type homeobox 1a
Symbol
cdx1a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in animal organ development; anterior/posterior pattern specification; and retinoic acid receptor signaling pathway. Predicted to localize to nucleus. Is expressed in several structures, including intestinal bulb; margin; mesoderm; neuroectoderm; and tail bud. Orthologous to human CDX1 (caudal type homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdx1a Human Ortholog
No data available
Associated With cdx1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000047 Helix-turn-helix motif
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR006820 Caudal-like activation domain
Domain IPR020479 Homeobox domain, metazoa
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Caudal-like activation domain Helix-turn-helix motif Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:Q8AXR4 228
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations