ZFIN Image: Lakowski et al., 2007, Fig. S3

Image

Figure Caption

Fig. S3 The zebrafish Pax6a BAC transgene exhibits differential promoter activity in the adult mouse retina. DsRed is expressed by a subset of EGFP⁺ cells in the adult mouse retina. Both EGFP and DsRed were visualized by indirect immunofluorescence (EGFP, green; DsRed, red). Arrowheads denote examples of EGFP⁺/DsRed- cells. Horizontal and ganglion cells express EGFP but not DsRed. DsRed is expressed by a subset of EGFP⁺ cells in the both the GCL and INL. Marker analyses presented in this study showed that GABAergic amacrine cells express both DsRed and EGFP; DsRed expressing neurites tend to localize to the middle strata of the IPL (arrow in B). A subset of bipolar cells also coexpresses DsRed and EGFP.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 307(2), Lakowski, J., Majumder, A., and Lauderdale, J.D., Mechanisms controlling Pax6 isoform expression in the retina have been conserved between teleosts and mammals, 498-520, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.