ZFIN Image: Nambiar et al., 2007, Fig. 6

Image

Figure Caption

Fig. 6 The col locus encodes hdac1. col maps close to the zebrafish hdac1 locus on LG 19 (A). A schematic showing the genomic organization of the zebrafish hdac1 gene (B). The zebrafish hdac1 gene has 15 exons and 14 introns spanning 9.94 kb of the genome and a T–G transversion in the intronic sequence adjacent to exon 5 causes aberrant splicing between exons 4 and 5 in col mutants (C). Aberrantly spliced hdac1 cDNA fragment in col with an additional 9 bp running in lane 1 can be distinguished from the wildtype product running in lane 2 (D). hdac1 expression is unaffected in 2 dpf col mutants (F, H) compared to wildtype (E and G).

Figure Data

Expression / Labeling details

Acknowledgments

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Reprinted from Mechanisms of Development, 124(9-10), Nambiar, R.M., Ignatius, M.S., and Henion, P.D., Zebrafish colgate/hdac1 functions in the non-canonical Wnt pathway during axial extension and in Wnt-independent branchiomotor neuron migration, 682-698, Copyright (2007) with permission from Elsevier. Full text @ Mech. Dev.