ZFIN Image: Schlueter et al., 2007, Fig. S1

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Figure Caption

Fig. S1 The igf1ra and igf1rb receptor subtypes are ubiquitously expressed in zebrafish embryos. (A–D) Whole-mount mRNA in situ hybridization for igf1ra (A, C) and igf1rb (B, D). Panels C and D present high magnification (400×) images of the respective genital ridge regions (indicted with boxes in panels A and B). Genital ridge boundaries are denoted by the dashed lines. (E–F) Primordial germ cells (PGCs) in genital ridges of the respective embryos, identified by whole-mount fluorescence immunohistochemistry with Vasa antibody. Panels G and H present merged images of C–E and D–F, respectively. Both receptor subtypes are expressed uniformly throughout the embryos, including the PGCs and genital ridges.

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Acknowledgments

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Reprinted from Developmental Biology, 305(1), Schlueter, P.J., Sang, X., Duan, C., and Wood, A.W., Insulin-like growth factor receptor 1b is required for zebrafish primordial germ cell migration and survival, 377-387, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.