Gene

kif23

ID

ZDB-GENE-991019-4

Name

kinesin family member 23

Symbol

kif23 Nomenclature History

Previous Names

cb738 (1)
knsl5 (1)
mklp1
wu:fi30e02
wu:fi39f08

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Involved in cytoskeleton-dependent cytokinesis; embryonic cleavage; and vesicle transport along microtubule. Localizes to several cellular components, including cleavage furrow; microtubule; and nucleus. Is expressed in proliferative region. Orthologous to human KIF23 (kinesin family member 23).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb738 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kif23 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
congenital dyserythropoietic anemia type III	Alliance	Anemia, congenital dyserythropoietic, type IIIA	105600

Associated With kif23 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019821	Kinesin motor domain, conserved site
Domain	IPR001752	Kinesin motor domain
Domain	IPR032384	Kinesin-like protein Kif23, Arf6-interacting domain
Family	IPR027640	Kinesin-like protein
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily
Homologous_superfamily	IPR038105	Kinesin-like protein Kif23, Arf6-interacting domain superfamily

Domain Details Per Protein

Protein	Length	Kinesin-like protein	Kinesin-like protein Kif23, Arf6-interacting domain	Kinesin-like protein Kif23, Arf6-interacting domain superfamily	Kinesin motor domain	Kinesin motor domain, conserved site	Kinesin motor domain superfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M9P0Y6 InterPro	967
UniProtKB:A0A8M9PLX5 InterPro	982
UniProtKB:A0A286Y967 InterPro	882
UniProtKB:Q9PUU5 InterPro	867

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kif23-201 (1) Ensembl	Ensembl	3,191 nt	Select Tool
mRNA	kif23-202 (1) Ensembl	Ensembl	1,198 nt	Select Tool
mRNA	kif23-203 (1) Ensembl	Ensembl	4,135 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-kif23	polyclonal	kif23		Rabbit	IHC		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations