Gene
srfa
- ID
- ZDB-GENE-990714-29
- Name
- serum response factor a
- Symbol
- srfa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Human ortholog(s) of this gene implicated in cardiomyopathy and lymphangioleiomyomatosis. Is expressed in several structures, including adaxial cell; digestive system; musculature system; pericardial region; and pleuroperitoneal region. Orthologous to human SRF (serum response factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | MADS-box/MEF2 Transcription Factor | MADS SRF-like | Transcription factor, MADS-box | Transcription factor, MADS-box superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BLC6
|
482 | ||||
|
UniProtKB:A8HAM3
|
539 |
Interactions and Pathways
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-srfa | polyclonal | Rabbit |
|
Santa Cruz Biotechnology, Inc.
|
3 |
Plasmids
No data available