Gene

tenm3

ID

ZDB-GENE-990714-19

Name

teneurin transmembrane protein 3

Symbol

tenm3 Nomenclature History

Previous Names

cb399 (1)
id:ibd3379
odd Oz/ten-m homolog 3 (1)
odz3 (1)
seizure resistant s334 (1)
srs334 (1)
tenascin-M3 (1)
zgc:153720

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have cell adhesion molecule binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in dendrite guidance; retinal ganglion cell axon guidance; and visual perception. Predicted to localize to integral component of plasma membrane and neuron projection. Is expressed in several structures, including fin bud; immature eye; mesoderm; nervous system; and neural tube. Orthologous to human TENM3 (teneurin transmembrane protein 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

18 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb399 (23 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tenm3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Microphthalmia, syndromic 15	615145
		?Microphthalmia/coloboma 9	615145

Associated With tenm3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR009471	Teneurin intracellular, N-terminal
Domain	IPR022385	Rhs repeat-associated core
Domain	IPR028916	Tox-GHH domain
Family	IPR051216	Teneurin domain-containing protein
Homologous_superfamily	IPR008969	Carboxypeptidase-like, regulatory domain superfamily
Homologous_superfamily	IPR011042	Six-bladed beta-propeller, TolB-like
Repeat	IPR006530	YD repeat
Repeat	IPR031325	RHS repeat

Domain Details Per Protein

Protein	Length	Carboxypeptidase-like, regulatory domain superfamily	EGF-like domain	RHS repeat	Rhs repeat-associated core	Six-bladed beta-propeller, TolB-like	Teneurin domain-containing protein	Teneurin intracellular, N-terminal	Tox-GHH domain	YD repeat
UniProtKB:Q9W7R4 InterPro	2694

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tenm3-201 (1) Ensembl	Ensembl	1,469 nt	Select Tool ZFIN BLAST
mRNA	tenm3-202 (1) Ensembl	Ensembl	8,515 nt	Select Tool ZFIN BLAST
mRNA	tenm3-204 (1) Ensembl	Ensembl	11,289 nt	Select Tool ZFIN BLAST
mRNA	tenm3-206 (1) Ensembl	Ensembl	8,719 nt	Select Tool ZFIN BLAST
mRNA	tenm3-207 (1) Ensembl	Ensembl	2,890 nt	Select Tool ZFIN BLAST
ncRNA	tenm3-203 (1) Ensembl	Ensembl	627 nt	Select Tool ZFIN BLAST
ncRNA	tenm3-205 (1) Ensembl	Ensembl	653 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-tenm3		tenm3		Rabbit	IHC		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations