Gene

otpb

ID
ZDB-GENE-990708-7
Name
orthopedia homeobox b
Symbol
otpb Nomenclature History
Previous Names
  • otp1 (1)
  • otp
  • otpa
  • cb977 (1)
  • otp a
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in forebrain neuron development; hypothalamus development; and mammillary body development. Predicted to localize to nucleus. Is expressed in several structures, including brain; gonad; neural keel; neural plate; and neurons. Orthologous to human OTP (orthopedia homeobox).
Genome Resources
Note
None
Expression
All Expression Data
50 figures from 20 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With otpb Human Ortholog
No data available
Associated With otpb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000047 Helix-turn-helix motif
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR003654 OAR domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Helix-turn-helix motif Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily OAR domain
UniProtKB:B0S6A5 315
UniProtKB:A0A2R8Q301 302
UniProtKB:Q6DGH9 315
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations