Gene

ncam1a

ID

ZDB-GENE-990415-31

Name

neural cell adhesion molecule 1a

Symbol

ncam1a Nomenclature History

Previous Names

ncam1
ncam
zNCAM (1)
fj56g09
wu:fj56g09 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Acts upstream of or within posterior commissure morphogenesis. Predicted to be located in plasma membrane. Is expressed in several structures, including anterior neural keel; myotome; nervous system; optic vesicle; and pectoral fin. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; bipolar disorder; drug dependence; middle cerebral artery infarction; and nicotine dependence. Orthologous to human NCAM1 (neural cell adhesion molecule 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

27 figures from 12 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d828 (14 images)
eu303 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Langhauser et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ncam1a Human Ortholog

No data available

Associated With ncam1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Family	IPR009138	Neural cell adhesion
Family	IPR050958	Cell Adhesion and Cytoskeletal Organization
Family	IPR051170	Neural and epithelial cell adhesion domain-containing protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M2B821	InterPro	989
UniProtKB:A0A8M2B824	InterPro	978
UniProtKB:A0A8M3B4M6	InterPro	994
UniProtKB:A0A8M2B827	InterPro	749
UniProtKB:A0A8M3ATS9	InterPro	1010
UniProtKB:A0A8M3ALE2	InterPro	1000
UniProtKB:A0A8M2B8D1	InterPro	988
UniProtKB:A0A8M3AWT0	InterPro	652
UniProtKB:A0A8M6YUF3	InterPro	727
UniProtKB:A0A8M2B851	InterPro	717
UniProtKB:B3DH85	InterPro	837
UniProtKB:A0A8M6Z3L2	InterPro	995
UniProtKB:A0A8M3AM36	InterPro	869
UniProtKB:A0A8M2B837	InterPro	1005
UniProtKB:A0A8M6Z2Y4	InterPro	854
UniProtKB:A0AB32TEF7	InterPro	852
UniProtKB:A0AB32TEL3	InterPro	732
UniProtKB:A0AB32TEP5	InterPro	993
UniProtKB:A0AB32TG64	InterPro	983

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ncam1a-201 (1) Ensembl	Ensembl	2,921 nt	Select Tool ZFIN BLAST
mRNA	ncam1a-202 (1) Ensembl	Ensembl	878 nt	Select Tool ZFIN BLAST
mRNA	ncam1a-206 (1) Ensembl	Ensembl	2,810 nt	Select Tool ZFIN BLAST
mRNA	ncam1a-207 (1) Ensembl	Ensembl	2,840 nt	Select Tool ZFIN BLAST
ncRNA	ncam1a-002 (1) Ensembl	Ensembl	903 nt	Select Tool ZFIN BLAST
ncRNA	ncam1a-004 (1) Ensembl	Ensembl	665 nt	Select Tool ZFIN BLAST
ncRNA	ncam1a-005 (1) Ensembl	Ensembl	528 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations