ZFIN ID: ZDB-GENE-990415-278
Gene Name: wingless-type MMTV integration site family, member 10a
Gene Symbol: wnt10a    Nomenclature History

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Previous Name: etID309718.9 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have cytokine activity and frizzled binding activity. Involved in odontogenesis. Predicted to localize to extracellular space. Is expressed in caudal fin and nervous system. Human ortholog(s) of this gene implicated in Schopf-Schulz-Passarge syndrome and tooth agenesis. Orthologous to human WNT10A (Wnt family member 10A).
Genome Resources: Alliance (1),  Gene:30171 (1),  Ensembl(GRCz11):ENSDARG00000017155 (1)
GENE EXPRESSION
All Expression Data: 19 figures from 16 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
DISEASE ASSOCIATED WITH wnt10a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Schopf-Schulz-Passarge syndrome Alliance Schopf-Schulz-Passarge syndrome 224750
tooth agenesis Alliance Tooth agenesis, selective, 4 150400
Odontoonychodermal dysplasia 257980
DISEASE ASSOCIATED WITH wnt10a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process odontogenesis (more)
Cellular Component extracellular region (more)
Molecular Function signaling receptor binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA wnt10a-201 (1)    Ensembl 1608
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-wnt10a polyclonal Rabbit WB Aviva Systems Biology
2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM wnt10a No data available
MARKER RELATIONSHIPS
wnt10a Contained in: [BAC] DKEY-31M21 (1) (order this)
wnt10a Encodes: [cDNA] MGC:194456 (1), MGC:194458 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_130980 (1)
Genomic GenBank:CR847976 (1) 222676 nt Blast at MegaBLAST
Polypeptide UniProtKB:B0V1G8 (1) 442 aa
Sequence Information (all 17)
ORTHOLOGY for wnt10a ( Chr: 9 )
CITATIONS (68)