Gene

wnt10a

ID

ZDB-GENE-990415-278

Name

wingless-type MMTV integration site family, member 10a

Symbol

wnt10a Nomenclature History

Previous Names

etID309718.9 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within odontogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in caudal fin and nervous system. Human ortholog(s) of this gene implicated in Schopf-Schulz-Passarge syndrome; ectodermal dysplasia; and tooth agenesis. Orthologous to human WNT10A (Wnt family member 10A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

22 figures from 19 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Yuan et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wnt10a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Schopf-Schulz-Passarge syndrome	Alliance	Schopf-Schulz-Passarge syndrome	224750
tooth agenesis	Alliance	Tooth agenesis, selective, 4	150400
		Ectodermal dysplasia 16 (odontoonychodermal dysplasia)	257980

Associated With wnt10a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018161	Wnt protein, conserved site
Family	IPR005817	Wnt
Family	IPR013302	Wnt-10 protein
Homologous_superfamily	IPR043158	Wnt, C-terminal domain