Gene
wnt10a
- ID
- ZDB-GENE-990415-278
- Name
- wingless-type MMTV integration site family, member 10a
- Symbol
- wnt10a Nomenclature History
- Previous Names
-
- etID309718.9 (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have frizzled binding activity. Involved in odontogenesis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in Schopf-Schulz-Passarge syndrome and tooth agenesis. Is expressed in caudal fin and nervous system. Orthologous to human WNT10A (Wnt family member 10A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Yuan et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Schopf-Schulz-Passarge syndrome | Alliance | Schopf-Schulz-Passarge syndrome | 224750 |
| tooth agenesis | Alliance | Tooth agenesis, selective, 4 | 150400 |
| Ectodermal dysplasia 16 (odontoonychodermal dysplasia) | 257980 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt-10 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:B0V1G8
|
442 | ||||
|
UniProtKB:P43446
|
442 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wnt10a-201
(1)
|
Ensembl | 1,608 nt | ||
| mRNA |
wnt10a-202
(1)
|
Ensembl | 1,051 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-wnt10a | polyclonal | Rabbit |
|
Aviva Systems Biology
|
2 |
Plasmids
No data available