Gene

foxn4

ID
ZDB-GENE-990415-277
Name
forkhead box N4
Symbol
foxn4 Nomenclature History
Previous Names
  • whn
  • sli
  • slipjig
  • whna (1)
  • winged helix nude
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in atrioventricular canal development and heart looping. Acts upstream of or within heart valve development; positive regulation of transcription, DNA-templated; and regulation of heart contraction. Predicted to be active in nucleus. Is expressed in several structures, including forebrain neural keel; nervous system; optic vesicle; pericardial region; and presumptive neural retina. Orthologous to human FOXN4 (forkhead box N4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxn4 Human Ortholog
No data available
Associated With foxn4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Fork head domain Fork head domain conserved site 2 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A2BGM5 550
UniProtKB:O13032 142
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations