Gene
fzd2
- ID
- ZDB-GENE-990415-224
- Name
- frizzled class receptor 2
- Symbol
- fzd2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have Wnt-activated receptor activity and Wnt-protein binding activity. Involved in several processes, including Wnt signaling pathway, calcium modulating pathway; heart development; and sensory epithelium regeneration. Localizes to plasma membrane. Is expressed in several structures, including cardiovascular system; fin; head; head mesenchyme; and mesoderm. Human ortholog(s) of this gene implicated in omodysplasia. Orthologous to human FZD2 (frizzled class receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 18 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb383 (18 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
omodysplasia 2 | Alliance | Omodysplasia 2 | 164745 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Frizzled cysteine-rich domain superfamily | Frizzled domain | Frizzled/secreted frizzled-related protein | Frizzled/Smoothened, 7TM | GPCR, family 2-like, 7TM |
---|---|---|---|---|---|---|
UniProtKB:Q90YL7
|
550 |
Interactions and Pathways
No data available
Plasmids
No data available