Gene

mef2aa

ID
ZDB-GENE-990415-163
Name
myocyte enhancer factor 2aa
Symbol
mef2aa Nomenclature History
Previous Names
  • mef2a
  • etID309779.18 (1)
  • wu:fd19d02
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Enables transcription cis-regulatory region binding activity. Acts upstream of or within several processes, including myofibril assembly; positive regulation of macromolecule metabolic process; and somitogenesis. Predicted to be located in nucleus. Is expressed in cardiovascular system; myotome; nervous system; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mef2aa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
coronary artery disease Alliance {Coronary artery disease, autosomal dominant, 1} 608320
Associated With mef2aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002100 Transcription factor, MADS-box
Domain IPR022102 Holliday junction regulator protein family C-terminal
Domain IPR033896 MADS MEF2-like
Homologous_superfamily IPR036879 Transcription factor, MADS-box superfamily
Domain Details Per Protein
Protein Length Holliday junction regulator protein family C-terminal MADS MEF2-like Transcription factor, MADS-box Transcription factor, MADS-box superfamily
UniProtKB:Q1LXH4 524
UniProtKB:A0A2R8QU09 467
UniProtKB:Q1LXH3 487
UniProtKB:Q1LXH5 488
UniProtKB:A0A0R4IRM3 460
UniProtKB:A0A2R8QIE4 459
UniProtKB:Q2MJS9 462
UniProtKB:Q1LXH6 458
UniProtKB:A0A2R8QMZ5 459
UniProtKB:Q98868 460
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-mef2 polyclonal IgG Rabbit
  • IHC
AnaSpec
4
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations