Gene

hoxb9a

ID
ZDB-GENE-990415-109
Name
homeobox B9a
Symbol
hoxb9a Nomenclature History
Previous Names
  • hoxb9
  • BZ-23
  • bz23
  • wu:fc06b03
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in embryonic skeletal system morphogenesis; positive regulation of transcription by RNA polymerase II; and regionalization. Predicted to localize to nucleus. Is expressed in CNS interneuron; paraxial mesoderm; and spinal cord neural tube. Orthologous to human HOXB9 (homeobox B9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la015133TgTransgenic insertionUnknownUnknownDNA
sa14877Allele with one point mutationUnknownPremature StopENU
sa17045Allele with one point mutationUnknownMissense, Splice SiteENU
sa31325Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-hoxb9aN/ASundaramoorthi et al., 2023
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Human Disease
Associated With hoxb9a Human Ortholog
No data available
Associated With hoxb9a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR006711 Hox9, N-terminal activation domain
Domain IPR020479 Homeodomain, metazoa
Family IPR017112 Homeobox protein HXA9/HXB9/HXC9
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Domain Details Per Protein
Protein Length Abd-B homeobox transcription factor Homedomain-like superfamily Homeobox, conserved site Homeobox protein HXA9/HXB9/HXC9 Homeodomain Homeodomain, metazoa Hox9, N-terminal activation domain
UniProtKB:Q9PWM2 249
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 3
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hoxb9a-201 (1) Ensembl 2,577 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-72A16ZFIN Curated Data
EncodesESTfc06b03ZFIN Curated Data
EncodescDNAMGC:113834ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHOXB917
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
MouseHoxb911
Conserved genome location (synteny) (1)
Citations
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