Gene

acvr1ba

ID
ZDB-GENE-980526-527
Name
activin A receptor type 1Ba
Symbol
acvr1ba Nomenclature History
Previous Names
  • acvr1b
  • taram-a
  • tarama
  • alk4 (1)
  • axis
  • wu:fb75f01
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have activin binding activity and activin receptor activity, type I. Involved in dorsal/ventral pattern formation; fin regeneration; and formation of primary germ layer. Predicted to localize to activin receptor complex. Is expressed in several structures, including DEL; blastodisc; germ ring; margin; and presumptive shield. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ACVR1B (activin A receptor type 1B).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
text only from Jazwinska et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acvr1ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Pancreatic cancer, somatic
Associated With acvr1ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR003605 GS domain
Family IPR000333 Ser/Thr protein kinase, TGFB receptor
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length GS domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Ser/Thr protein kinase, TGFB receptor
UniProtKB:B3DJ37 505
UniProtKB:P79689 505
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations