ZFIN ID: ZDB-GENE-980526-527
Gene Name: activin A receptor type 1Ba
Gene Symbol: acvr1ba
Sequence Ontology ID : SO:0000704

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Previous Names: acvr1b, taram-a, tarama, alk4 (1), axis, wu:fb75f01

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including SMAD binding activity, activin binding activity, and growth factor binding activity; involved in several processes, including dorsal/ventral pattern  ...
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3475 Point Mutation Unknown Unknown ENU
hu3520 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa12061 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12247 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: text only from Jazwinska et al., 2007
    Observed in:
    DISEASE ASSOCIATED WITH acvr1ba HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Pancreatic cancer, somatic
    DISEASE ASSOCIATED WITH acvr1ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endodermal cell fate determination (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000333 (1)
  • InterPro:IPR000472 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR003605 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS51256 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF01064 (1)
  • Pfam:PF08515 (1)
  • EC:2.7.11.30 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acvr1ba-001 (1) 3789
    ncRNA acvr1ba-002 (1) 536
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acvr1ba
    MARKER RELATIONSHIPS
    acvr1baContained in: [BAC] CH211-169D8 (1) (order this)
    acvr1baEncodes: [EST] fb75f01
    [cDNA] MGC:194749 (1) (order this), MGC:194782 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130990 (1) 1518bp
    Genomic GenBank:CR387931 (1) 144701bp
    Select Tool
    Polypeptide UniProtKB:B3DJ37 (1) 505aa
    Sequence Clusters UniGene:75170 (1)
    Sequence Information (all 21)
    OTHER acvr1ba GENE PAGES
  • Alliance (1)
  • Gene:30183 (1)
  • VEGA:OTTDARG00000028141 (1)
  • Ensembl(GRCz11):ENSDARG00000018968 (2)
  • ORTHOLOGY for acvr1ba (Chr: 23)
    CITATIONS (64)