ZFIN ID: ZDB-GENE-980526-26
Gene Name: muscle segment homeobox 1b
Gene Symbol: msx1b    Nomenclature History

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Previous Names: msh-B, mshB, msxB, msxb (1), etID309829.1 (1), wu:fk04h02, zgc:110559

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic organ morphogenesis; fin regeneration; and regulation of neuron apoptotic process. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; fin; fin bud; germ ring; and median fin fold.
Genome Resources: Alliance (1),  Gene:30511 (1),  Ensembl(GRCz11):ENSDARG00000008886 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa39680 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-msx1b N/A 2
    MO2-msx1b N/A 1
    MO3-msx1b N/A 1
    MO4-msx1b N/A 1
    DISEASE ASSOCIATED WITH msx1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH msx1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA msx1b-201 (1)    Ensembl 1424
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-msx monoclonal IgG1 , k Mouse IHC Developmental Studies Hybridoma Bank
    5
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM msx1b
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-6.5msx1b:EGFP) msx1b EGFP Danio rerio 1 5
    Tg(msx1b:EGFP) msx1b EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    msx1b Contained in: [BAC] DKEYP-80C12 (1)
    msx1b Encodes: [EST] fk04h02 (1)
    [cDNA] MGC:110559 (1), MGC:192593 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131260 (1) 1414 nt
    Genomic GenBank:CR812943 (1) 225846 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B2GSG0 (1) 257 aa
    Sequence Information (all 21)
    ORTHOLOGY for msx1b ( Chr: 1 )
    CITATIONS (131)