Gene
cdh11
- ID
- ZDB-GENE-980526-170
- Name
- cadherin 11, type 2, OB-cadherin (osteoblast)
- Symbol
- cdh11 Nomenclature History
- Previous Names
-
- cdhvn
- ventral neural cadherin
- vnc
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable cadherin binding activity and calcium ion binding activity. Acts upstream of or within otolith development; retina development in camera-type eye; and retinal ganglion cell axon guidance. Predicted to be located in plasma membrane. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Is expressed in cleithrum; nervous system; optic vesicle; and pectoral fin bud. Human ortholog(s) of this gene implicated in Elsahy-Waters syndrome and Teebi hypertelorism syndrome 2. Orthologous to human CDH11 (cadherin 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Elsahy-Waters syndrome | Alliance | Elsahy-Waters syndrome | 211380 |
| Teebi hypertelorism syndrome 2 | Alliance | Teebi hypertelorism syndrome 2 | 619736 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily | Cadherin, Y-type LIR-motif | Catenin binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B3DGG4
|
800 |
Interactions and Pathways
No data available
Plasmids
No data available