Gene

ccne1

ID
ZDB-GENE-980526-168
Name
cyclin E1
Symbol
ccne1 Nomenclature History
Previous Names
  • ccne (1)
  • cyce (1)
  • fa18e07
  • wu:fa18e07 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits kinase activity. Predicted to contribute to protein kinase activity. Predicted to be involved in G1/S transition of mitotic cell cycle and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to several cellular components, including centrosome; cyclin E1-CDK2 complex; and nucleus. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Is expressed in anterior axial hypoblast; intestine; nervous system; notochord; and polster. Orthologous to human CCNE1 (cyclin E1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
33 figures from 24 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccne1 Human Ortholog
No data available
Associated With ccne1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR048258 Cyclins, cyclin-box
Domain IPR004367 Cyclin, C-terminal domain
Domain IPR006671 Cyclin, N-terminal
Domain IPR013763 Cyclin-like domain
Family IPR039361 Cyclin
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin Cyclin, C-terminal domain Cyclin-like domain Cyclin-like superfamily Cyclin, N-terminal Cyclins, cyclin-box
UniProtKB:P47794 410
UniProtKB:B2GQF9 410
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ccne1-201 (1) Ensembl 2,372 nt
mRNA ccne1-203 (1) Ensembl 2,114 nt
ncRNA ccne1-003 (1) Ensembl 701 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations