Gene
kcna2a
- ID
- ZDB-GENE-131113-1
- Name
- potassium voltage-gated channel, shaker-related subfamily, member 2a
- Symbol
- kcna2a Nomenclature History
- Previous Names
-
- Kv1.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have voltage-gated potassium channel activity. Involved in sleep. Predicted to localize to voltage-gated potassium channel complex. Is expressed in head.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Srdanovic et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 32 | Alliance | Developmental and epileptic encephalopathy 32 | 616366 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Domain | IPR003131 | Potassium channel tetramerisation-type BTB domain |
| Domain | IPR005821 | Ion transport domain |
| Family | IPR003968 | Potassium channel, voltage dependent, Kv |
| Family | IPR003972 | Potassium channel, voltage dependent, Kv1 |
| Family | IPR004049 | Potassium channel, voltage dependent, Kv1.2 |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | Ion transport domain | Potassium channel tetramerisation-type BTB domain | Potassium channel, voltage dependent, Kv | Potassium channel, voltage dependent, Kv1 | Potassium channel, voltage dependent, Kv1.2 | SKP1/BTB/POZ domain superfamily | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F8M2
|
493 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-kcna2 | polyclonal | Rabbit |
|
Novus Biologicals, LLC
|
2 |
Plasmids
No data available
- Comparative Orthology
- Alliance