ZFIN is now using GRCz12tu for Genomic Data
Gene
slc19a1
- ID
- ZDB-GENE-110401-1
- Name
- solute carrier family 19 member 1
- Symbol
- slc19a1 Nomenclature History
- Previous Names
-
- fj80b07
- im:7144090
- wu:fj80b07
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable folate:monoatomic anion antiporter activity and folic acid binding activity. Predicted to be involved in folate transmembrane transport. Predicted to act upstream of or within vitamin transport. Predicted to be located in membrane. Predicted to be active in apical plasma membrane and basolateral plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; cleft lip; dextro-looped transposition of the great arteries; hematologic cancer; and malaria. Orthologous to human SLC19A1 (solute carrier family 19 member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Liang et al., 2024
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 114 | Alliance | Immunodeficiency 114, folate-responsive | 620603 |
| ?Megaloblastic anemia, folate-responsive | 601775 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | MFS transporter superfamily | Reduced folate carrier |
|---|---|---|---|---|
| UniProtKB:E7F2A7 | InterPro | 528 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc19a1-201
(1)
|
Ensembl | 2,139 nt | ||
| mRNA |
slc19a1-202
(1)
|
Ensembl | 3,199 nt | ||
| mRNA |
slc19a1-203
(1)
|
Ensembl | 2,161 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers