Gene

ccl25b

ID
ZDB-GENE-110222-2
Name
chemokine (C-C motif) ligand 25b
Symbol
ccl25b Nomenclature History
Previous Names
  • ccl21
  • CCL-chr11a (1)
  • dr-chr11-CCL21-36.7%-DN (1)
  • Dr11_WGA839_1_159228 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Enables chemokine activity. Acts upstream of or within lymphoid lineage cell migration into thymus; regulation of hematopoietic stem cell migration; and regulation of hematopoietic stem cell proliferation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including blood vessel; head; hematopoietic system; immune system; and spinal cord. Orthologous to human CCL25 (C-C motif chemokine ligand 25).
Genome Resources
Note
I-Na Lu et al. (120807-5) suggest orthology to CCL21 based on AA similarity and CL with human Chr 9.
Comparative Information
Expression
All Expression Data
9 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Xue et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccl25b Human Ortholog
No data available
Associated With ccl25b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001811 Chemokine interleukin-8-like domain
Family IPR039809 Chemokine beta/gamma/delta
Homologous_superfamily IPR036048 Chemokine interleukin-8-like superfamily
Domain Details Per Protein
Protein Length Chemokine beta/gamma/delta Chemokine interleukin-8-like domain Chemokine interleukin-8-like superfamily
UniProtKB:A9ZPF2 106
UniProtKB:F1QBE9 106
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations