Gene

terf1

ID
ZDB-GENE-090612-2
Name
telomeric repeat binding factor (NIMA-interacting) 1
Symbol
terf1 Nomenclature History
Previous Names
  • wu:fb74c04
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Enables telomeric DNA binding activity. Predicted to be involved in negative regulation of nucleobase-containing compound metabolic process and telomere maintenance via telomerase. Predicted to act upstream of or within telomere maintenance. Predicted to be located in nucleus. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Orthologous to human TERF1 (telomeric repeat binding factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Wagner et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa24459Allele with one point mutationUnknownPremature StopENU
sa32480Allele with one point mutationUnknownSplice SiteENU
whu308Allele with one deletionUnknownUnknownCRISPR
whu309Allele with one deletionUnknownUnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-terf1Ma et al., 2022
MO1-terf1N/AHuang et al., 2013
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Human Disease
Associated With terf1 Human Ortholog
No data available
Associated With terf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001005 SANT/Myb domain
Domain IPR017930 Myb domain
Family IPR017357 Telomeric repeat-binding factor 1/2
Family IPR052450 Telomeric Repeat-Binding Domain-Containing Protein
Homologous_superfamily IPR009057 Homedomain-like superfamily
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Domain Details Per Protein
Protein Length Homedomain-like superfamily Myb domain SANT/Myb domain Telomere repeat-binding factor, dimerisation domain superfamily Telomeric Repeat-Binding Domain-Containing Protein Telomeric repeat-binding factor 1/2
UniProtKB:A0A8N7TFE0 379
UniProtKB:A0A8M9PXV3 386
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 24
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA terf1-201 (1) Ensembl 1,543 nt
mRNA terf1-202 (1) Ensembl 909 nt
mRNA terf1-204 (1) Ensembl 2,900 nt
ncRNA terf1-003 (1) Ensembl 667 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-171B20ZFIN Curated Data
Contained inBACDKEY-192J17ZFIN Curated Data
EncodesESTfb74c04
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTERF18
Amino acid sequence comparison (2)
Phylogenetic tree (1)
Conserved genome location (synteny) (1)
MouseTerf11
Phylogenetic tree (1)
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
Citations
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