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Gene

cpe

ID
ZDB-GENE-090313-68
Name
carboxypeptidase E
Symbol
cpe Nomenclature History
Previous Names
  • si:ch211-198g9.2
  • zgc:85981
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process and protein processing. Predicted to act upstream of or within proteolysis. Predicted to be active in extracellular space. Is expressed in posterior pancreatic bud and retina. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CPE (carboxypeptidase E).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cpe Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder and hypogonadotropic hypogonadism 619326
Associated With cpe Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000834 Peptidase M14, carboxypeptidase A
Homologous_superfamily IPR008969 Carboxypeptidase-like, regulatory domain superfamily
Domain Details Per Protein
Protein Length Carboxypeptidase-like, regulatory domain superfamily Peptidase M14, carboxypeptidase A
UniProtKB:Q6NSM5
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations