Gene
cpe
- ID
- ZDB-GENE-090313-68
- Name
- carboxypeptidase E
- Symbol
- cpe Nomenclature History
- Previous Names
-
- si:ch211-198g9.2
- zgc:85981
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process and protein processing. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in posterior pancreatic bud and retina. Orthologous to human CPE (carboxypeptidase E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Klingbeil et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| BDV syndrome | 619326 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Carboxypeptidase E, carboxypeptidase domain | Carboxypeptidase-like, regulatory domain superfamily | Peptidase M14, carboxypeptidase A | Peptidase M14 domain-containing protein |
|---|---|---|---|---|---|
|
UniProtKB:Q6NSM5
|
Interactions and Pathways
No data available
Plasmids
No data available