ZFIN is now using GRCz12tu for Genomic Data
Gene
lca5
- ID
- ZDB-GENE-090313-268
- Name
- lebercilin LCA5
- Symbol
- lca5 Nomenclature History
- Previous Names
-
- si:dkey-241o6.2
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Involved in photoreceptor cell maintenance; photoreceptor cell outer segment organization; and protein localization to photoreceptor outer segment. Predicted to be located in centrosome and cilium. Predicted to be active in axoneme. Used to study Leber congenital amaurosis. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 5. Orthologous to human LCA5 (lebercilin LCA5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from Qu et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Leber congenital amaurosis 5 | Alliance | Leber congenital amaurosis 5 | 604537 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Leber congenital amaurosis | lca5zf3156/zf3156 | standard conditions | Qu et al., 2019 |
Domain, Family, and Site Summary
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers