ZFIN ID: ZDB-FISH-210202-4
Fish name: lca5zf3156/zf3156
Genotype: lca5zf3156/zf3156
Targeting Reagent: none
HUMAN DISEASE MODELED by lca5zf3156/zf3156
Human Disease Conditions Citations
Leber congenital amaurosis standard conditions Qu et al., 2019
GENE EXPRESSION
Gene expression in lca5zf3156/zf3156
Reporter gene expression No data available
PHENOTYPE
Phenotype in lca5zf3156/zf3156
Phenotype Conditions Figures
blue sensitive photoreceptor cell cone photoreceptor outer segment decreased length, abnormal standard conditions Fig. S5 from Qu et al., 2019
blue sensitive photoreceptor cell cone photoreceptor outer segment degenerate, abnormal standard conditions Fig. 5 from Qu et al., 2019
blue sensitive photoreceptor cell cone photoreceptor outer segment morphology, normal standard conditions Fig. S8 from Qu et al., 2019
cilium assembly process quality, normal standard conditions Fig. 8 from Qu et al., 2019
eye decreased functionality, abnormal standard conditions Fig. 2 from Qu et al., 2019
eye photoreceptor cell cilium ift88 expression increased distribution, abnormal standard conditions Fig. 8 from Qu et al., 2019
eye photoreceptor cell cilium length, normal standard conditions Fig. 8 from Qu et al., 2019
eye photoreceptor cell photoreceptor inner segment gnat1 expression mislocalised, abnormal standard conditions Fig. 7 from Qu et al., 2019
green sensitive photoreceptor cell cone photoreceptor outer segment decreased length, abnormal standard conditions Fig. S5 from Qu et al., 2019
green sensitive photoreceptor cell cone photoreceptor outer segment degenerate, abnormal standard conditions Fig. 5 from Qu et al., 2019
green sensitive photoreceptor cell cone photoreceptor outer segment morphology, normal standard conditions Fig. S8 from Qu et al., 2019
photoreceptor cell cilium ift88 expression increased amount, abnormal standard conditions Fig. 8 from Qu et al., 2019
photoreceptor outer segment layer cone photoreceptor disc membrane fragmented, abnormal standard conditions Fig. 4 from Qu et al., 2019
photoreceptor outer segment layer rod photoreceptor outer segment disorganized, abnormal standard conditions Fig. 4Fig. S4 from Qu et al., 2019
red sensitive photoreceptor cell cone photoreceptor outer segment decreased length, abnormal standard conditions Fig. S5 from Qu et al., 2019
red sensitive photoreceptor cell cone photoreceptor outer segment degenerate, abnormal standard conditions Fig. 5 from Qu et al., 2019
red sensitive photoreceptor cell cone photoreceptor outer segment morphology, normal standard conditions Fig. S7 from Qu et al., 2019
red sensitive photoreceptor cell photoreceptor inner segment opn1lw1 expression mislocalised, abnormal standard conditions Fig. 6 from Qu et al., 2019
retina morphology, normal standard conditions Fig. 3 from Qu et al., 2019
retina detection of electrical stimulus involved in electroception disrupted, abnormal standard conditions Fig. 2 from Qu et al., 2019
retinal cone cell degeneration, abnormal standard conditions Fig. 3 from Qu et al., 2019
retinal cone cell cone photoreceptor outer segment degenerate, abnormal standard conditions Fig. S6 from Qu et al., 2019
retinal outer nuclear layer opn1lw1 expression mislocalised, abnormal standard conditions Fig. 6 from Qu et al., 2019
retinal outer plexiform layer opn1lw1 expression mislocalised, abnormal standard conditions Fig. 6 from Qu et al., 2019
retinal photoreceptor layer morphology, abnormal standard conditions Fig. 3 from Qu et al., 2019
retinal rod cell rod photoreceptor outer segment degenerate, abnormal standard conditions Fig. 5 from Qu et al., 2019
retinal rod cell rod photoreceptor outer segment length, normal standard conditions Fig. 5 from Qu et al., 2019
retinal rod cell rod photoreceptor outer segment morphology, normal standard conditions Fig. S6 from Qu et al., 2019
UV sensitive photoreceptor cell cone photoreceptor outer segment decreased length, abnormal standard conditions Fig. S5 from Qu et al., 2019
UV sensitive photoreceptor cell cone photoreceptor outer segment degenerate, abnormal standard conditions Fig. 5 from Qu et al., 2019
UV sensitive photoreceptor cell cone photoreceptor outer segment morphology, normal standard conditions Fig. S8 from Qu et al., 2019

CITATIONS  (1)