Gene
nectin1a
- ID
- ZDB-GENE-090224-1
- Name
- nectin cell adhesion molecule 1a
- Symbol
- nectin1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable cell adhesion mediator activity. Acts upstream of or within primary palate development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including hindbrain; mandibular arch skeleton; optic vesicle; solid lens vesicle; and visual system. Human ortholog(s) of this gene implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia. Orthologous to human NECTIN1 (nectin cell adhesion molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Liu et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cleft lip-palate-ectodermal dysplasia syndrome | Alliance | Cleft lip/palate-ectodermal dysplasia syndrome | 225060 |
| cleft lip-palate-ectodermal dysplasia syndrome | Alliance | Orofacial cleft 7 | 225060 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Length |
|---|---|
|
UniProtKB:A0A8M2B818
|
479 |
|
UniProtKB:A0A8M2B8A6
|
496 |
|
UniProtKB:B0JYH7
|
475 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nectin1a-201
(1)
|
Ensembl | 783 nt | ||
| mRNA |
nectin1a-202
(1)
|
Ensembl | 1,796 nt |
Interactions and Pathways
No data available
Plasmids
No data available