Gene

nrg2b

ID
ZDB-GENE-090205-2
Name
neuregulin 2b
Symbol
nrg2b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have signaling receptor binding activity. Predicted to be involved in animal organ development and intracellular signal transduction. Predicted to localize to extracellular space. Is expressed in brain; neurons; and spinal cord. Orthologous to human NRG2 (neuregulin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Honjo et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nrg2b Human Ortholog
No data available
Associated With nrg2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR002154 Neuregulin, C-terminal
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Family IPR040180 Neuregulin
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length EGF-like domain Immunoglobulin domain subtype Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype 2 Neuregulin Neuregulin, C-terminal
UniProtKB:A0A8M3AZM3 701
UniProtKB:E7FGA4 705
UniProtKB:A0A8M2B373 697
UniProtKB:B9VQL5 599
UniProtKB:A0A8M3B5L8 705
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript nrg2b-204 (1) Ensembl 798 nt
mRNA nrg2b-201 (1) Ensembl 1,873 nt
mRNA nrg2b-202 (1) Ensembl 4,186 nt
mRNA nrg2b-203 (1) Ensembl 529 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations