Gene
nckap1l
- ID
- ZDB-GENE-080204-117
- Name
- NCK associated protein 1 like
- Symbol
- nckap1l Nomenclature History
- Previous Names
-
- zgc:172352 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to contribute to Rac GTPase binding activity. Predicted to be involved in several processes, including cell projection assembly; cortical actin cytoskeleton organization; and neuron projection morphogenesis. Predicted to localize to SCAR complex. Orthologous to human NCKAP1L (NCK associated protein 1 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Castro et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 72 | Alliance | Immunodeficiency 72 with autoinflammation | 618982 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR019137 | Nck-associated protein 1 |
Domain Details Per Protein
| Protein | Length | Nck-associated protein 1 |
|---|---|---|
|
UniProtKB:A9JRH8
|
1123 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nckap1l-201
(1)
|
Ensembl | 3,372 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-nckap1l | polyclonal | Rabbit |
|
Thermo Fisher Scientific (Lab Vision)
|
1 |
Plasmids
No data available