Gene

lrrn1

ID
ZDB-GENE-071126-1
Name
leucine rich repeat neuronal 1
Symbol
lrrn1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Acts upstream of or within olfactory nerve formation and olfactory placode morphogenesis. Predicted to be located in membrane. Predicted to be active in extracellular matrix and extracellular space. Is expressed in basal plate midbrain region; hindbrain neural keel; nervous system; neural plate; and somite. Orthologous to human LRRN1 (leucine rich repeat neuronal 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Garaffo et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lrrn1 Human Ortholog
No data available
Associated With lrrn1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000483 Cysteine-rich flanking region, C-terminal
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Family IPR050328 Multifunctional Developmental and Immune Receptor
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Cysteine-rich flanking region, C-terminal Fibronectin type III Fibronectin type III superfamily Immunoglobulin domain subtype Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype 2 Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype Multifunctional Developmental and Immune Receptor
UniProtKB:A9JRH0
InterPro
717
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lrrn1-201 (1)
Ensembl
Ensembl 3,497 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-lrrn1 monoclonal IgG1 , k Mouse
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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